Why not to use punch biopsies in formalin-fixed paraffin-embedded samples of prostate cancer tissue for DNA and RNA extraction?
نویسندگان
چکیده
Abstract Extraction of DNA and RNA from formalin-fixed paraffin-embedded (FFPE) tissue blocks is a critical process in molecular oncology testing. Using FFPE, it possible to choose the portion study, taking into account cell morphology, storage stability conditions at room temperature, make retrospective studies with clinical pathological information. In prostate cancer tissue, contrast macroscopic tumors, not easy identify tumor; therefore, very important microscopic diagnosis. We do recommend punching this because can normal for analysis. present article we review differences between punch biopsy microdissection.
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ژورنال
عنوان ژورنال: African Journal of Urology
سال: 2021
ISSN: ['2090-2379', '1110-5704', '1961-9987']
DOI: https://doi.org/10.1186/s12301-021-00257-4